Waterjet cut print

 Printed (detail); the holes have embossed nicely.

Printed (detail); the holes have embossed nicely.

 The underside.

The underside.

 Inked up and ready to print.

Inked up and ready to print.

 The water jet cut steel plate, before filing, polishing and sanding. The image originates from an earlier screen print.

The water jet cut steel plate, before filing, polishing and sanding. The image originates from an earlier screen print.

More screen printing

 Studio wall. Standing back to look. Two patterns, two scales.

Studio wall. Standing back to look. Two patterns, two scales.

 Homemade molecular ruler - testing and talking

Homemade molecular ruler - testing and talking

 Individually dotting the dots - for NSQ100 pattern

Individually dotting the dots - for NSQ100 pattern

 Laser cut dots placed by hand on a hand made grid. Varying levels of precision. Ready to be exposed onto the screen. Pattern scaled up by 10.

Laser cut dots placed by hand on a hand made grid. Varying levels of precision. Ready to be exposed onto the screen. Pattern scaled up by 10.

Dynamic flow

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 Talking about how molecules might move as a dynamic matrix, sticking, locking and clustering around obstacles.

Talking about how molecules might move as a dynamic matrix, sticking, locking and clustering around obstacles.

Nano fabrication

 The clean room.

The clean room.

 Patterns on nine glass slides, set onto a silicon wafer which has been spin-coated with a polymer resin, ready for electrobeam lithography.

Patterns on nine glass slides, set onto a silicon wafer which has been spin-coated with a polymer resin, ready for electrobeam lithography.

 After electrobeam lithography the glass slides are removed from the wafer and a developer is used to remove the polymer strands cut by the laser, to reveal the pattern. There are so many different kinds of tweezers in this room. 

After electrobeam lithography the glass slides are removed from the wafer and a developer is used to remove the polymer strands cut by the laser, to reveal the pattern. There are so many different kinds of tweezers in this room. 

 Paul and I review the resulting patterns on the scanning electron microscope (SEM) 

Paul and I review the resulting patterns on the scanning electron microscope (SEM) 

 One of the new patterns - each dot is 70 nanometers in diameter : that's 0.00007mm (!)

One of the new patterns - each dot is 70 nanometers in diameter : that's 0.00007mm (!)

Thought experiment

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 After talking with Nikolaj, Paul and Marie, I'm working on a series of new dot patterns with a particular theory to test out.. 

After talking with Nikolaj, Paul and Marie, I'm working on a series of new dot patterns with a particular theory to test out.. 

Communication highs and lows

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 Last week Marie and I had what we thought at the time was a revelatory discussion and drawing session about measurements and possibilities - discussing the way intergrins pair up and connect with each other around the nanopits. We got really excited about one particular realisation.. high fives all round. Until we got back to the office, discussed a bit more and realised we'd both talking about slightly different things... back to the drawing board.. 

Last week Marie and I had what we thought at the time was a revelatory discussion and drawing session about measurements and possibilities - discussing the way intergrins pair up and connect with each other around the nanopits. We got really excited about one particular realisation.. high fives all round. Until we got back to the office, discussed a bit more and realised we'd both talking about slightly different things... back to the drawing board.. 

Made up arrangements

Talking about integrin pairing around an obstacle

 Talking about integrins and how they might arrange themselves around pits. They won't actually look anything like this but it's interesting to draw and sparks questions about symmetry, measurement and dynamics.

Talking about integrins and how they might arrange themselves around pits. They won't actually look anything like this but it's interesting to draw and sparks questions about symmetry, measurement and dynamics.

 Nikolaj: 'you've drawn the way the molecules arrange themselves in the space that's available' 

Nikolaj: 'you've drawn the way the molecules arrange themselves in the space that's available' 

 What happens when two sets of arrangements meet?

What happens when two sets of arrangements meet?

Topographic geometries

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 More measuring drawings; from one nanopit to another, then between NSQ50 and NSQ100 dot arrangements, furthest and nearest configurations. Raising questions in the group and even inspiring some graphs in response... and words like Gaussian, Lorentzian and intra-cell contact points.

More measuring drawings; from one nanopit to another, then between NSQ50 and NSQ100 dot arrangements, furthest and nearest configurations. Raising questions in the group and even inspiring some graphs in response... and words like Gaussian, Lorentzian and intra-cell contact points.

Proteins: arranging and measuring

 Arranging pairs of proteins, measuring distances (guessing, imagining, questioning)

Arranging pairs of proteins, measuring distances (guessing, imagining, questioning)

 Conversations about intergrins and how they might behave.. Nikolaj asks for a drawing.

Conversations about intergrins and how they might behave.. Nikolaj asks for a drawing.

 Sketching out ideas: measurements between things.

Sketching out ideas: measurements between things.

 Thinking about density of measurements in a disordered arrangement of dots.

Thinking about density of measurements in a disordered arrangement of dots.

Ways of Seeing

It's easier/more interesting/provoking to talk about the interaction of substrate and biology, now we have the screenprints to look at. 'They're exactly what we're working on except 50,000 times bigger' says Nikolaj. Nice to have a different format to see things with.

 Nikolaj uses his hands/fingertips to explain his ideas about possible ways the molecules might be behaving around the geometry of their environment.

Nikolaj uses his hands/fingertips to explain his ideas about possible ways the molecules might be behaving around the geometry of their environment.

 Paul talks about the relative scale of nano pits / molecules /tent pegs using coffee (the driving force behind most of our conversations)

Paul talks about the relative scale of nano pits / molecules /tent pegs using coffee (the driving force behind most of our conversations)

 Marie and Paul figuring out how to correlate data with the screenprints, to test out hypotheses... (there's a piece of acetate on that screen he's drawing on...) 

Marie and Paul figuring out how to correlate data with the screenprints, to test out hypotheses... (there's a piece of acetate on that screen he's drawing on...) 

 And it does actually kind of work

And it does actually kind of work

Screenprints

Started playing with layering hex and square grids using screenprinting

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Studio wall

 Hex + hex. Marie says 'You can really see a macro structure emerging...'

Hex + hex. Marie says 'You can really see a macro structure emerging...'

 Overlaying square and hex, and differentiating with colour... zig zags emerge again and thinking about pattern/line v colour. Talking with Nikolaj and Marie about what the two matrices represent.

Overlaying square and hex, and differentiating with colour... zig zags emerge again and thinking about pattern/line v colour. Talking with Nikolaj and Marie about what the two matrices represent.

 Screens with dot grids exposed

Screens with dot grids exposed

Sketchbook: Sq v Hex

I've been wondering about/drawing the differences between the square and hexagonal nanopit patterns used in different research projects.

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 Found some dot stickers which are exactly the right diameter to replicate the ratios of Paul's 'classic' dot grids. 

Found some dot stickers which are exactly the right diameter to replicate the ratios of Paul's 'classic' dot grids. 

Lino cuts

Lino cuts based on drawings I've been thinking about about for a while, since initial conversations with Prof Gadegaard about the controlled disorder dot patterns. Nice to be able to go back to them and make prints now. 

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Nikolaj: "They actually tell two stories: 1) This is how we form the displacements you have been drawing. 2) The sequence is actually how the electron beam lithography machine works."

So many variables

Was great talking to Marie Cutiongco about her research into stem cell response to different dot patterns. She showed me around the lab and how to take pics of her dots through the microscope.. I need some practice to get clearer images...

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 Ordered and less ordered grids

Ordered and less ordered grids

Getting started

I have a desk in an office shared with three amazing people whose work I'm trying to get my head around... Lots of conversations about patterns and how cells respond to them.. Why have they chosen these patterns to work with? How are they made? Talking to Paul Reynolds about the grid patterns used in various ongoing bioengineering projects.. comparing my drawn versions and his algorithm-generated formations. 

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 Sketchbook drawings - ways of placing randomised dots within a grid

Sketchbook drawings - ways of placing randomised dots within a grid

 Paul's simulations

Paul's simulations