Proteins: arranging and measuring

 Arranging pairs of proteins, measuring distances (guessing, imagining, questioning)

Arranging pairs of proteins, measuring distances (guessing, imagining, questioning)

 Conversations about intergrins and how they might behave.. Nikolaj asks for a drawing.

Conversations about intergrins and how they might behave.. Nikolaj asks for a drawing.

 Sketching out ideas: measurements between things.

Sketching out ideas: measurements between things.

 Thinking about density of measurements in a disordered arrangement of dots.

Thinking about density of measurements in a disordered arrangement of dots.

Ways of Seeing

It's easier/more interesting/provoking to talk about the interaction of substrate and biology, now we have the screenprints to look at. 'They're exactly what we're working on except 50,000 times bigger' says Nikolaj. Nice to have a different format to see things with.

 Nikolaj uses his hands/fingertips to explain his ideas about possible ways the molecules might be behaving around the geometry of their environment.

Nikolaj uses his hands/fingertips to explain his ideas about possible ways the molecules might be behaving around the geometry of their environment.

 Paul talks about the relative scale of nano pits / molecules /tent pegs using coffee (the driving force behind most of our conversations)

Paul talks about the relative scale of nano pits / molecules /tent pegs using coffee (the driving force behind most of our conversations)

 Marie and Paul figuring out how to correlate data with the screenprints, to test out hypotheses... (there's a piece of acetate on that screen he's drawing on...) 

Marie and Paul figuring out how to correlate data with the screenprints, to test out hypotheses... (there's a piece of acetate on that screen he's drawing on...) 

 And it does actually kind of work

And it does actually kind of work

Screenprints

Started playing with layering hex and square grids using screenprinting

 Studio wall

Studio wall

 Hex + hex. Marie says 'You can really see a macro structure emerging...'

Hex + hex. Marie says 'You can really see a macro structure emerging...'

 Overlaying square and hex, and differentiating with colour... zig zags emerge again and thinking about pattern/line v colour. Talking with Nikolaj and Marie about what the two matrices represent.

Overlaying square and hex, and differentiating with colour... zig zags emerge again and thinking about pattern/line v colour. Talking with Nikolaj and Marie about what the two matrices represent.

 Screens with dot grids exposed

Screens with dot grids exposed

Sketchbook: Sq v Hex

I've been wondering about/drawing the differences between the square and hexagonal nanopit patterns used in different research projects.

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 Found some dot stickers which are exactly the right diameter to replicate the ratios of Paul's 'classic' dot grids. 

Found some dot stickers which are exactly the right diameter to replicate the ratios of Paul's 'classic' dot grids. 

Lino cuts

Lino cuts based on drawings I've been thinking about about for a while, since initial conversations with Prof Gadegaard about the controlled disorder dot patterns. Nice to be able to go back to them and make prints now. 

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Nikolaj: "They actually tell two stories: 1) This is how we form the displacements you have been drawing. 2) The sequence is actually how the electron beam lithography machine works."

So many variables

Was great talking to Marie Cutiongco about her research into stem cell response to different dot patterns. She showed me around the lab and how to take pics of her dots through the microscope.. I need some practice to get clearer images...

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 Ordered and less ordered grids

Ordered and less ordered grids

Getting started

I have a desk in an office shared with three amazing people whose work I'm trying to get my head around... Lots of conversations about patterns and how cells respond to them.. Why have they chosen these patterns to work with? How are they made? Talking to Paul Reynolds about the grid patterns used in various ongoing bioengineering projects.. comparing my drawn versions and his algorithm-generated formations. 

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 Sketchbook drawings - ways of placing randomised dots within a grid

Sketchbook drawings - ways of placing randomised dots within a grid

 Paul's simulations

Paul's simulations